Cannabis sativa is one of the most useful and versatile plants on the planet. Not only can the cannabis plant be used to produce industrial fibre, food, and fuel, it can treat a variety of different medical conditions.
The cannabis plant is an effective medical treatment for certain conditions because of the “cannabinoids” that it contains. Cannabinoids are chemical compounds that can bind with cannabinoid receptors in the human body. This process can have a positive affect on medical conditions ranging from glaucoma through to multiple sclerosis and epilepsy.
The most well known cannabinoid is tetrahydrocannabinol (THC), which delivers the “high” associated with ingesting or smoking cannabis. However, researchers have discovered that another cannabinol, called cannabidiol(CBD), may be most powerful component of cannabis for medicinal use. This article will take a closer look at cannabidiol to help you understand the potential health benefits obtained form using it.
How do Cannabinoids work?
The term “Cannabinoids” refers to a group of natural and man-made chemicals. These chemicals can interact with cannabinoid receptors that are located in different locations throughout the body including the central nervous system, eyes, and immune system.
Cannabinoid receptors are a part of the “Endocannabinoid system” that controls many physiological processes includingpain-sensation, mood, energy metabolism, heart function, appetiteand memory. The brain creates its own set of cannabinoids to help the body perform these essential tasks. Scientists have identified two types of cannabinoids receptors so far:
- Cannabinoid receptor type 1 (CB1)
This receptor is primarily found in the brain and nervous system, including the basal ganglia and parts of the limbic system. Researchers have also found them in the retina, anterior eye, and the reproductive system of both men and women. They are also found on the nerve endings of neurones in the brain, which is why scientists think they can be used to treat degenerative brain diseases.
- Cannabinoid receptor type 2 (CB2)
Most CB2receptors are in the immune system or cells created by the immune system. There are large populations of CB2receptors in the spleen and throughout the nervous system. Scientists have also discovered CB2being expressed by a subpopulation of microglia in the human cerebellum. Researchers believe that the CB2 receptor is responsible for the anti-inflammatory effect of some cannabinoids.
Cannabis is absolutely packed with cannabinoids — researchers have already identified more than 113 cannabinoids in the cannabis plant at this point (Aizpurua-Olaizola et al., 2017). When a product containing cannabinoids is consumed, they attach to receptors on cells and change the behaviour of the cell. The cannabinoids in cannabis have the capacity to alter immune system function, change how neurones in the brain behave and much more.
While some of the cannabinoids in cannabis cause a psychoactive reaction (like THC), most do not. Some cannabinoids, like cannabinol, actually reduce the psychoactive effect of THC, calming the high that is experienced when consuming cannabis.
Researchers are still attempting to understand how the various cannabinoids affect the human body. The most common cannabinoids found in cannabis are:
THC mostly affects the CB1 receptors in the brain, which is why is has such a strong psychoactive effect. Researchers have discovered it is quite useful for providing pain relief and decreasing nausea.
- Cannabidiol (CBD)
Cannabidiol is a very powerful cannabinoid that has no psychoactive effects. Scientists believe this form cannabinoid can calm the nervous system, treat psychological problems, and be used to treat certain brain disorders.
- Cannabichromene (CBC)
The third most-common cannabinoid in cannabis, CBC has strong anti-depressant, anti-inflammatory, anti-fungal, and anti-tumour capabilities. It can also encourage brain growth by stimulating neurogenesis.
- Cannabigerol (CBG)
This another non-psychoactive cannabinoid found in cannabis. Researchers suspect it may be useful for reducing intra-ocular pressure in the eye and treating glaucoma.
What are the potential medicinal uses of cannabidiol (CBD)?
There have already been hundreds of research papers published discussing the potential medicinal benefits of cannabinoids. The conditions which may be treated with cannabis range from ADHD through to Tourette’s Syndrome.
Researchers are particularly excited about CBD because of its powerful anti-inflammatory properties and capacity to protect neurones (nerve cells in the brain). The medicinal properties of CBD identified so far include (Fernández-Ruiz et al., 2013):
- Anti-emetic — It is capable of reducing nausea and vomiting
- Anticonvulsant — Suppresses seizure activity
- Antipsychotic — CDC combats psychosis disorders
- Anti-inflammatory — Which is useful for treating a wide range of inflammatory conditions
- Anti-oxidant — Which may be useful for combatting neurodegenerative disorders
- Anti-tumoural /Anti-cancer — It helps the body target tumours and cancer cells
- Anxiolytic/Anti-depressant — Potential for treating mental illness
The illnesses and medical ailments that may be treated with CBD include:
- Bacterial infections
- Epilepsy and other illnesses causing seizures
- Neurodegenerative diseases
- Cardiovascular disease
- Oxidative injury
- Vomiting and nausea
- Anxiety, depression, schizophrenia and other mental illnesses
CBD may also be used to treat cancer, however, researchers are still investigating how effective and safe it is to use. There is substantial evidence that CBD may be useful for aggressively targeting tumours and preventing them from spreading.
How is cannabidiol produced and consumed?
The best way to obtain high-potency CBD is to extract oil from the stalks and seeds of cannabis (hemp) plants. Oil produced using this method is naturally low in the psychoactive constituents of cannabis, but high in CBD.
Producers of CBD hemp oil use cannabiscultivars that are naturally low in THC and high in CBD, further improving the quality of the products being produced. It is a 100% natural botanical extract without any artificial additives.
CBD hemp oil is also an excellent nutritional supplement that is high in amino acids, omega-3 fatty acids, vitamins, and other cannabinoids including cannabigerol (CBG), cannabidivarian (CBCV) and cannabinol (CBN).
CBD hemp oil can be consumed in many ways including capsules, drops, food supplements, and topical creams. It is simple to take and can greatly improve your health!
You can read more about the products that are available here.
For more information on CBD hemp oil and the products that are available, please contact us on 666-777-888.
Aizpurua-Olaizola, O., Soydaner, U., Öztürk, E., Schibano, D., Simsir, Y., & Navarro, P. et al. (2017). Evolution of the Cannabinoid and Terpene Content during the Growth ofCannabis sativaPlants from Different Chemotypes. Retrieved 8 February 2017, fromhttp://pubs.acs.org/doi/abs/10.1021/acs.jnatprod.5b00949
Cannabinoid receptor. (2017). En.wikipedia.org. Retrieved 8 February 2017, from https://en.wikipedia.org/wiki/Cannabinoid_receptor
Fernández-Ruiz, J., Sagredo, O., Pazos, M., García, C., Pertwee, R., Mechoulam, R., & Martínez-Orgado, J. (2013). Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?. British Journal Of Clinical Pharmacology, 75(2), 323-333. http://dx.doi.org/10.1111/j.1365-2125.2012.04341.x